Acetaminophen
(ass-cet-ah-MEE-noe-fen)
Trade Name(s):
Acephen
Suppositories 120 mgSuppositories
325 mgSuppositories
650 mg
Aceta
Tablets 325 mgTablets
500 mgElixir 120 mg/5 mL
Acetaminophen Uniserts
Suppositories 120 mgSuppositories
325 mgSuppositories
650 mg
Apacet
Tablets, chewable 80 mg
Solution 100 mg/mL
Aspirin Free Anacin Maximum Strength
Tablets 500 mgCaplets
500 mgGelcaps 500 mg
Aspirin Free Pain Relief
Tablets 325 mgTablets
500 mgCaplets 500 mg
Children's Dynafed Jr.
Tablets, chewable 80 mg
Children's Feverall
Suppositories 120 mgTablets, chewable 120 mgCapsules, sprinkle
80 mg
Children's Genapap
Tablets, chewable 80 mg
Elixir 160 mg/5 mL
Children's Halenol
Liquid 160 mg/5 mL
Children's Mapap
Tablets, chewable 80 mg
Elixir 160 mg/5 mL
Children's Pain Reliever
Elixir 160 mg/5 mLSuspension
160 mg/5 mL
Children's Panadol
Tablets, chewable 80 mg
Liquid 160 mg/5 mL
Children's Silapap
Elixir 80 mg/2.5 mL
Children's Tylenol
Tablets, chewable 80 mg
Elixir 160 mg/5 mL
Children's Tylenol Soft Chews
Tablets, chewable 80 mg
Dapacin
Capsules 325 mg
Extra Strength Dynafed E.X.
Tablets 500 mg
Feverall, Junior Strength
Suppositories 325 mgCapsules, sprinkle 160 mg
Feverall, Infants
Suppositories 80 mg
Genapap
Tablets 325 mg
Genapap, Infants' Drops
Solution 100 mg/mL
Genapap Extra Strength
Tablets 500 mgCaplets
500 mg
Genebs
Tablets 325 mg
Genebs Extra Strength
Tablets 500 mgCaplets
500 mg
Infants' Pain Reliever
Drops 80 mg/0.8 mL
Infants' Silapap
Solution 100 mg/mL
Junior Strength Panadol
Caplets 160 mg
Liquiprin Drops for Children
Solution 80 mg/1.66 mL
Mapap Extra Strength
Tablets 500 mg
Mapap Infant Drops
Solution 100 mg/mL
Mapap Regular Strength
Tablets 325 mg
Maranox
Tablets 325 mg
Meda Cap
Capsules 500 mg
Meda Tab
Tablets 325 mg
Neopap
Suppositories 125 mg
Oraphen-PD
Elixir 120 mg/5 mL
Panadol
Tablets 500 mgCaplets
500 mg
Panadol, Infants' Drops
Solution 100 mg/mL
Redutemp
Tablets 500 mg
Ridenol
Elixir 80 mg/5 mL
Tapanol Extra Strength
Tablets 500 mgCaplets
500 mgGelcaps 500 mg
Tapanol Regular Strength
Tablets 325 mg
Tempra
Tablets 160 mg
Tempra 1
Solution 100 mg/mL
Tempra 2 Syrup
Liquid 160 mg/5 mL
Tempra 3
Tablets, chewable 80 mg
Tylenol Arthritis
Tablets, extended-release 650 mg
Tylenol Caplets
Tablets 325 mg
Tylenol Extended Relief
Caplets 650 mg
Tylenol Extra Strength
Tablets 500 mgGelcaps
500 mgLiquid 500 mg/15 mL
Tylenol Infants' Drops
Solution 100 mg/mL
Tylenol Junior Strength
Tablets 160 mg
Tylenol Regular Strength
Tablets 325 mg
Uni-Ace
Solution 100 mg/mL
Abenol
A.F. Anacin
Apo-Acetaminophen
Atasol
Children's Acetaminophen
Children's Chewable Acetaminophen
Extra Strength Acetaminophen
Pediatrix
PMS-Acetaminophen
Regular Strength Acetaminophen
Tempra
222AF
Tylenol
Indicates Canadian trade names.
Class: AnalgesicAntipyretic
Action:
Inhibits prostaglandins in CNS but lacks anti-inflammatory effects in periphery; reduces fever through direct action on hypothalamic heat-regulating center.
Indications:
Relief of mild-to-moderate pain; treatment of fever.
Unlabeled use(s): Pain and fever prophylaxis after vaccination.
Contraindications:
Standard considerations.
Route/Dosage:
Oral
Adults:
PO
325 to 650 mg prn q 4 to 6 hr or 1 g 3 to 4 times/day. Do not exceed 4 g/day.
Children:
PO
10 to 15 mg/kg dose prn q 4 to 6 hr; do not exceed 5 doses/24 hr.
Suppositories
Adults:
PR
650 mg q 4 to 6 hr; do not exceed 6 suppositories/24 hr.
Children: 3 to 6 yr:
PR
120 mg q 4 to 6 hr; do not exceed 720 mg/24 hr.
Children: 6 to 12 yr:
PR
325 mg q 4 to 6 hr; do not exceed 2.6 g/24 hr.
Interactions:
Ethanol:
Chronic excessive use may increase risk of hepatotoxicity.
Hydantoins, sulfinpyrazone:
May decrease therapeutic effect of APAP; concomitant long-term use may increase risk of hepatotoxicity.
Lab Test Interferences:
With Chemstrip bG, Dextrostix,
Visidex II home blood glucose measurement systems, drug may cause
> 20% decrease in mean glucose.
Adverse Reactions:
- HEMA:
- Hemolytic anemia; neutropenia; leukopenia; pancytopenia; thrombocytopenia.
- HEPA:
- Jaundice.
- OTHER:
- Hypoglycemia; allergic skin eruptions or fever.
Precautions:
Pregnancy:
Category B.
Lactation:
Excreted in breast milk.
Hepatic impairment:
Chronic alcoholics should not exceed 2 g/day.
Persistent pain or fever:
May indicate serious illness. Consult health care provider.
Patient Care Considerations
Administration/Storage:
- Administer with water 30 min before or 2 hr after meals.
- Store tablets and capsules at room temperature in tightly closed container. Refrigerate suppositories. Refrigeration of elixir improves palatability.
Assessment/Interventions:
- Obtain patient history, including drug history and any known allergies.
- Assess for pain and fever before and 1 to 2 hr after administration.
- Assess serum glucose and liver enzyme levels before long-term therapy.
OVERDOSAGE: SIGNS & SYMPTOMS
Nausea, vomiting, abdominal pain, diarrhea, anorexia, malaise, diaphoresis, confusion, low BP, cardiac arrhythmias, jaundice, acute renal failure, liver failure
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Patient/Family Education:
- Instruct family to consult health care provider for use in children
< 3 yr and, not to continue taking drug > 5 days unless advised by health care provider.
- Instruct adult patients not to continue taking drug > 10 days for pain or 3 days for fever.
- Instruct patient/family to contact health care provider if pain or fever (> 103°F) persists > 3 days.
- Advise diabetic patients to use sugar-free form of drug.
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